MMR Analyte Control
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- For Research Use Only
- Not for Use with Agilent Antibodies
Staining MMR with Agilent Antibodies – Click Here
| Cell Line | MLH1 | MSH2 | MSH6 | PMS2 |
| A | Intact | Intact | Intact | Intact |
| B | Loss | Intact | Intact | Loss |
| C | Intact | Loss | Loss | Intact |
| D | Intact | Intact | Loss | Intact |
HistoCyte Laboratories’ MMR-A Analyte Control contains four different cell lines with loss of and intact staining for MLH1, PMS2, MSH2 and MSH6. This control is intended for assessment of reagent and instrument performance only. These cell lines are derived from the following tumors:
Cell line A: Breast adenocarcinoma
Cell line B: Prostate carcinoma
Cell line C: Colon adenocarcinoma
Cell line D: Colon adenocarcinoma
- Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
- Sections are cut at 4 µm, mounted on positively charged slides and dried overnight at 37ºC.
- Cell microarrays (CMA) contain cores that are 1.5-2.0 mm in diameter and 3.0-3.5 mm in length. It is possible to obtain over 300 sections depending on thickness.
