MMR Analyte Control
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- For Research Use Only
- 4 Cores, A: intact expression for MLH1/PMS2/MSH2/MSH6, B: loss of MLH1/PMS2 expression, C: loss of MSH2/MSH6, D: loss of MSH6 expression
HistoCyte Laboratories’ MMR Analyte Control consists of four different cell lines with loss of and intact expression for MLH1, PMS2, MSH2 and MSH6. This product is a convenient quality control solution being suitable for use with all the MMR assays, regardless of which assay is used. These cell lines are derived from the following tumors:
Cell line A: Breast adenocarcinoma
Cell line B: Prostate carcinoma
Cell line C: Colon adenocarcinoma
Cell line D: Colon adenocarcinoma
- Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
- Sections are cut at 4µm, mounted on positively charged slides and dried overnight at 37ºC.
- Cell microarrays (CMA) contain cores that are 1.5-2mm in diameter and 3-3.5mm in length. It is possible to obtain over 300 sections depending on thickness.