MMR Analyte Control

Mismatch Repair (MMR) Histology Slide Image

    • For Research Use Only
    • 4 Cores, A: intact expression for MLH1/PMS2/MSH2/MSH6, B: loss of MLH1/PMS2 expression, C: loss of MSH2/MSH6, D: loss of MSH6 expression

Product Options:

Part # HCL041 2 slides $33.00
Part # HCL042 5 slides $73.00
Part # HCL043 1 block $1,292.00

HistoCyte Laboratories’ MMR Analyte Control consists of four different cell lines with loss of and intact expression for MLH1, PMS2, MSH2 and MSH6. This product is a convenient quality control solution being suitable for use with all the MMR assays, regardless of which assay is used.  These cell lines are derived from the following tumors:

Cell line A: Breast adenocarcinoma

Cell line B: Prostate carcinoma

Cell line C: Colon adenocarcinoma

Cell line D: Colon adenocarcinoma

  1. Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
  2. Sections are cut at 4µm, mounted on positively charged slides and dried overnight at 37ºC.
  3. Cell microarrays (CMA) contain cores that are 1.5-2mm in diameter and 3-3.5mm in length.  It is possible to obtain over 300 sections depending on thickness.