Disinfectants

Coronavirus/COVID-19 News from Metrex:

March 13, 2020

Protocols for Disinfection Efficacy on COVID-19

As of the date of this writing, there is currently no EPA recognized test protocol to evaluate disinfection efficacy against this specific novel coronavirus virus strain, SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), which causes COVID-19 (Coronavirus Disease 2019). Therefore, there is no EPA-registered surface disinfectant that bears a label claim against SARS-CoV-2 as of the date of this writing.

All coronavirus strains are enveloped viral particles that belong to the same virus family of Coronaviridae. Enveloped viral particles are typically more susceptible to chemical disinfectant formulations than are other pathogens¹.

CDC’s interim recommendations for infection prevention and control now state that the use of EPA-registered, hospital-grade disinfectants are appropriate for SARS-CoV-2 in the healthcare settings.² The following Metrex products meet this guideline:

CaviWipes
CaviCide
CaviWipes1
CaviCide1

The CDC also refers to the EPA’s List N that lists EPA-registered disinfectants products with Emerging Viral Pathogens and Human Coronavirus claims for use against SARS-CoV-2. This list is actively being updated by the EPA to include additional disinfectants that meet EPA’s criteria.³

Refer to any updates on the EPA’s List N here:

www.epa.gov/pesticide-registration/list-n-disinfectants-use-against-sars-cov-2

The following Metrex products have been included onto the EPA’s List N:³

CaviCide ⁽⁸⁾
CaviWipes1 ⁽⁴⁾
CaviCide1 ⁽⁵⁾

The table below gives an overview of the information discussed above:

	Emerging Viral Pathogen Claim / Contact Time	EPA-registered, Hospital-Grade Disinfectant / Contact Time
CaviWipes	–	YES / 3 minutes
CaviCide	–	YES / 3 minutes
CaviWipes1	YES / 3 minutes	YES / 1 minute
CaviCide1	YES / 3 minutes	YES / 1 minute

REFERENCES:

Sattar, S. “Hierarchy of Susceptibility of Viruses to Environmental Surface Disinfectants: A Predictor of Activity Against new and Emerging Viral Pathogens”. Journal of AOAC International. 2007. Vol 90.6 https://www.researchgate.net/publication/5657319_Hierarchy_of_Susceptibility_of_Viruses_to_Environmental_Surface_Disinfectants A_Predictor_of_Activity_Against_New_and_Emerging_Viral_Pathogens. Accessed 3.3.2020.
Interim Infection Prevention and Control Recommendations for Patients with Confirmed Coronavirus Disease 2019 (COVID-19) or Persons Under Investigation for COVID-19 in Healthcare Settings. https://www.cdc.gov/coronavirus/2019-ncov/infection-control/control-recommendations.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fhcp%2Finfection-control.html. Accessed 3.11.2020.
List N: Disinfectants for Use Against SARS-CoV-2. https://www.epa.gov/pesticide-registration/list-n-disinfectants-use-against-sars-cov-2. Accessed 3.11.2020
CaviWipes1 Master Label from retrieved from EPA’s Pesticide Product and Label System. https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::NO::P8_PUID,P8_RINUM:504032,46781-13. Accessed 3.3.2020.
CaviCide1 Master Label from retrieved from EPA’s Pesticide Product and Label System. https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::NO::P8_PUID,P8_RINUM:503807,46781-12. Accessed 3.3.2020.
CaviWipes Bleach Master Label from retrieved from EPA’s Pesticide Product and Label System. https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::NO::P8_PUID,P8_RINUM:521508,46781-14. Accessed 3.3.2020.
CaviCide Bleach Master Label from retrieved from EPA’s Pesticide Product and Label System. https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::NO::P8_PUID,P8_RINUM:522158,46781-15. Accessed 3.3.2020.
CaviCide Master Label from retrieved from EPA’s Pesticide Product and Label System. https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::NO::P8_PUID,P8_RINUM:27348,46781-6. Accessed 3.3.2020.
Xu et. al., Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV, Viruses 2020, 12, 244, doi:10.3390/v12020244.

Link to Metrex website for more information