HPV/p16 Analyte Control

p16 HPV Histology Slide Image

    • For Research Use Only
    • Negative and positive expression of p16
    • 3 Cores with negative, mid and high HPV gene copies

Product Options:

Part # HCL004 2 slides $25.00
Part # HCL005 5 slides $56.00
Part # HCL006 1 block $882.00

HistoCyte Laboratories’ HPV/p16 Analyte Control contains 3 cell lines that demonstrate high, medium and negative expression of high-risk human papillomavirus types 16 and 18 by in situ hybridization (ISH).  The same cell lines also demonstrate high, intermediate (heterogeneous) and negative expression of p16 by immunohistochemistry (IHC).  Ideal for use as a same slide control for HPV ISH and p16 IHC to demonstrate assay efficacy.  These cell lines are derived from the following tumors:

Cell line A: Human breast adenocarcinoma

Cell line B: Human cervical adenocarcinoma

Cell line C: Human epidermoid carcinoma

  1. Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
  2. Sections are cut at 4µm, mounted on positively charged slides and dried overnight at 37ºC.
  3. Cell microarrays (CMA) contain cores that are 1.5-2mm in diameter and 3-3.5mm in length.  It is possible to obtain over 300 sections depending on thickness.