ALK-Lung Analyte Control

Anaplastic Lymphoma Kinase (ALK-1) Histology Slide Image

    • For Research Use Only
    • 2 Cores one negative and one positive for the EML4-ALK translocation and fusion protein

Product Options:

Part # HCL007 2 slides $17.00
Part # HCL008 5 slides $39.00
Part # HCL009 1 block $794.00

HistoCyte Laboratories’ ALK-Lung Analyte Control is a qualitative control containing two cell lines that demonstrate positive and negative expression of EML4-ALK. This fusion protein is commonly associated with lung cancer.  Ideal for use as a same slide control in immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to demonstrate the reagents have been correctly applied to the slide.  These cell lines are derived from the following tumors:

Cell line A: Breast Adenocarcinoma

Cell line B: Lung Adenocarcinoma

  1. Cells are fixed in 10% neutral buffered formalin and paraffin wax embedded.
  2. Sections are cut at 4µm, mounted on positively charged slides and dried overnight at 37ºC.
  3. Cell microarrays (CMA) contain cores that are 1.5-2mm in diameter and 3-3.5mm in length.  It is possible to obtain over 300 sections depending on thickness.