Immunohistochemistry by Innovex Biosciences
HISTO-STAT POLYMER 2-Step Staining System & Components

HISTO-STAT Alkaline Phosphatase Multivalent Polymer Kits
Multivalent, anti mouse & anti rabbit complete with chromogen of choice in large or small volume sizes.
HISTO-STAT Monovalent-Chicken Second Step Reagent (HRP)
for staining Chicken primary antibodies.
HISTO-STAT Monovalent-Goat Second Step Reagent (HRP)
for staining Goat primary antibodies.
HISTO-STAT Monovalent-Hamster Second Step Reagent (HRP)
for staining Hamster primary antibodies.
HISTO-STAT Monovalent-Mouse Second Step Reagent (HRP)
RAT ADSORBED for staining Mouse primary antibodies in Rat tissue.
HISTO-STAT Monovalent-Mouse Second Step Reagent (HRP)
for staining Mouse primary antibodies.
HISTO-STAT Monovalent-Rabbit Second Step Reagent (HRP)
for staining Rabbit primary antibodies.
HISTO-STAT Monovalent-Rat Second Step Reagent (HRP)
for staining Rat primary antibodies.
HISTO-STAT Monovalent-Rat Second Step Reagent (HRP)
MOUSE ADSORBED for staining Rat primary antibodies in Mouse tissue.
HISTO-STAT Monovalent-Sheep Second Step Reagent (HRP)
for staining Sheep primary antibodies.
HISTO-STAT Multivalent Second Step Reagent (Alk phos)
for staining both Mouse & Rabbit primary antibodies.
HISTO-STAT Multivalent Second Step Reagent (HRP)
for staining both Mouse & Rabbit primary antibodies.
HISTO-STAT Polymer Peroxidase Multivalent System-AEC Kit
HISTO-STAT Polymer Peroxidase Multivalent System-DAB Kit
Multivalent, anti mouse & anti rabbit complete with chromogen of choice in large or small volume sizes.
STAT-Q 3-STEP STAINING SYSTEM & COMPONENTS
STAT DOUBLE STAINING SYSTEM
Innovex STAT Double Staining Systems are suitable for staining two primary antibodies simultaneously in 3 easy steps. Apply both primaries at the same time, followed by the double stain second step reagent. Average cost per slide for STAT Double Staining System & primary antibodies is $7. Stains 350-450 slides. 3 year shelf life. Store at 4°C.
STAT-Q Alkaline Phosphatase Multivalent Complete Kit
STAT-Q Enzyme Labeled Streptavidin Alkaline Phosphatase Label
STAT-Q Enzyme Labeled Streptavidin Peroxidase (HRP) Label
STAT-Q Monovalent-Chicken Linking antibody
for staining Chicken primary antibodies.
STAT-Q Monovalent-Goat Linking antibody
for staining Goat primary antibodies.
STAT-Q Monovalent-Hamster Linking antibody
for staining Hamster primary antibodies.
STAT-Q Monovalent-Mouse Linking antibody
for staining Mouse primary antibodies.
STAT-Q Monovalent-Mouse Linking antibody RAT ADSORBED
for staining Mouse primary antibodies in Rat tissue.
STAT-Q Monovalent-Rabbit Linking antibody
for staining Rabbit primary antibodies.
STAT-Q Monovalent-Rat Linking antibody
for staining Rat primary antibodies.
STAT-Q Monovalent-Rat Linking antibody MOUSE ADSORBED
for staining Rat primary antibodies in Mouse tissue.
STAT-Q Monovalent-Sheep Linking antibody
for staining Sheep primary antibodies.
STAT-Q Mouse Adsorbed AEC Kit
for staining Rat Antibodies on Mouse Tissue
STAT-Q Mouse Adsorbed DAB Kit
for staining Rat Antibodies on Mouse Tissue
STAT-Q Multivalent Linking antibody
for staining both Mouse & Rabbit primary antibodies.
STAT-Q Peroxidase Multivalent System-AEC Kit

STAT-Q Peroxidase Multivalent System-DAB Kit
STAT-Q Rat Adsorbed AEC Kit
for staining Mouse Antibodies on Rat Tissue
STAT-Q Rat Adsorbed DAB Kit
for staining Mouse Antibodies on Rat Tissue
Primary Ab's
ACTH (Adrenocorticotrophic Hormone)
Actin, Muscle-Specific HHF35
Actin, Smooth Muscle Specific 1A4
Actinin, alpha
Adhesion Molecules
See CD markers, below.
Albumin
ALK-I
Alpha-1-Antichymotrypsin
Alpha-1-Antitrypsin
Alpha-1-Fetoprotein Monoclonal
Alpha-1-Fetoprotein Polyclonal
Amylase, pancreatic
Amyloid-Beta
See Beta-Amyloid, below.
Androgen Receptor
B cells
See CD markers, below.
bcl-10 Oncoprotein
bcl-2 Oncoprotein
bcl-2 Oncoprotein
bcl-6 Oncoprotein
Beta-2-Microglobulin
Bombesin
BRDU (Bromodeoxyuridine)
Breast Tumor Antigen (CA15-3)
Bromodeoxyuridine
See BRDU, above.
c-erB-2 Oncoprotein (Her-2/neu)
c-erB-2 Oncoprotein (Her-2/neu) Monoclonal
c-erB-3 Oncoprotein
CA125 (Ovarian Cancer Antigen)
CA15-3
See Breast Tumor Antigen, above.
CA19-9 (Sialyl Lewis a)
CA242 (Tumor Associated Mucin Antigen)
CA50 (Carcinoma Associated Mucin Antigen)
Calcitonin
Carcinoma Associated Mucin Antigen
See CA50, above.
Cathepsin B
Cathepsin D
Cathepsin G
Cathepsin H
CD10 (CALLA)
CD103
CD105 (Endoglin)
CD106 (VCAM) Vascular Cell Adhesion Molecule
CD117 (C-Kit)
CD11a, integrin a1(LFA-1a)
CD11b (Mac-1)
CD11c
CD13
CD138
CD14 (Monocytes/Macrophages)
CD15, Granulocytes (Reed Sternberg Cells)
CD16,Natural Killer Cells
CD18 (Integrin b2 Subunit)
CD1a,Thymocytes
CD2
CD20 (L26) B Cells
CD21
CD22
CD23
CD25 (Interleukin-2 Receptor)
CD27
CD29
CD3, Pan T cells
CD30, Ki-1 antigen (Reed Sternberg cells)
CD31, (PECAM) Adhesion Molecule
CD34 (Endothelial Cell Marker)
CD4,T Helper/Inducer
CD43
CD44 (HCAM) (Homing Receptor, Adhesion Molecule)
CD45 (LCA)
CD45RA, B cell
CD45RO (UCHL-1)
CD5,T Lymphocytes
CD51
CD54 (ICAM-1) Adhesion Molecule
CD56 (NCAM) (Neural Cell Adhesion Molecule)
CD57, Pan NK Cell Marker (Natural Killer Cells)
CD62E (ELAM-1) (E-selectin, Adhesion Molecule)
CD62L (L-selectin, LECAM-1)
CD62P (P-selectin)
CD68 Macrophage
CD7
CD71, Transferrin Receptor
CD79a, B Cells
CD8, Lymphocytes
CD83
CD99, MIC2 Gene Product Ewing's Sarcoma Marker
CEA (Carcinoembryonic antigen)
Chlamydia
Chorionic Gonadotropin (hCG)
Chorionic Gonadotropin Alpha Subunit (alpha-hCG)
Chorionic Gonadotropin Beta Subunit (Beta-hCG)
Chromogranin A
Chymase, Mast cell
Chymotrypsin
CMV (Cytomegalovirus)
See Cytomegalovirus, below.
Collagen Type I
Collagen Type II
Collagen Type III
Collagen Type IV
Collagen Type V
Collagen Type VI
Collagen Type VII
Colon Antigen, Lewis a
See CA19-9, above.
Common Acute Lymphoblastic Leukemia Antigen, CALLA
See CD10, above.
Complement C1q
Complement C3
Complement C4
Cyclin A
Cyclin B1
Cyclin D1
Cytokeratin (AE1/AE3) Blend
Cytokeratin (Pan Cytokeratin)
Cytokeratin 10
Cytokeratin 14
Cytokeratin 17
Cytokeratin 18
Cytokeratin 19
Cytokeratin 20
Cytokeratin 34bB4 (High MW, 68 kD)
Cytokeratin 34bE12 (High MW, 68, 58, 56.5 & 50 kD) (Prostate Marker)
Cytokeratin 5
Cytokeratin 5/6
Cytokeratin 7
Cytokeratin 8
Cytokeratin, acidic Low MW (AE1)
Cytokeratin, basic High MW (AE3)
Cytomegalovirus (CMV) Early and late proteins (blend)
Desmin
Dystrophin
E-Cadherin
EBV
See Epstein Barr Virus, below.
ELAM-1
See CD62E, above.
Endoglin
See CD105, above.
Endothelial Cells
See CD34, above.
Epidermal Growth Factor Receptor (EGFR)
Epithelial Membrane Antigen (EMA)
Epithelial Specific Antigen (ESA)
Epstein Barr Virus (EBV) Early and late protein
Estradiol
Estrogen Receptor (ER1D5)
Factor VIII (8) (von Willebrand Factor)
Factor XIII (13-a) (von Willebrand Factor)
Ferritin
Fibrinogen
Fibronectin
Filamin
Follicle Stimulating Hormone (FSH)
Gastrin
GFAP
See Glial Fibrillary Acidic Protein, below.
GI Tumor Marker (Sialyl Lewis a)
See CA19-9, above.
Glial Fibrillary Acidic Protein (GFAP)
Glucagon
Granular Membrane Protein
See CD62, above.
Growth Hormone (hGH)
HCAM,
Homing Receptor See CD44, above.
hCG
See Chorionic Gonadotropins, above.
Heat Shock Protein (HSP27)
Heat Shock Protein (HSP70)
Heat Shock Protein (HSP73)
Helicobacter Pylori
Hepatitis A
Hepatitis B Core Antigen (HBcAg)
Hepatitis B Surface Antigen (HBsAg)
Hepatitis C
Her-2/neu (c-erB-2 Oncoprotein)
Her-2/neu (c-erB-2 Oncoprotein) Monoclonal
Herpes Simplex Virus I & II (Blend)
hGH
See Growth Hormone, above.
HMB45, Melanoma
Homing Receptor
See CD44, above.
Human Milk Fat Globule
Human Papilloma Virus (HPV)
See Papilloma Virus, below.
ICAM-1
See CD54, above.
IgA, Human
IgD, Human
IgE, Human
IgG, Human
IgM, Human
Insulin
Integrins
See CD11a, CD18, above.
Interleukin-2 Receptor
See CD25, above.
Kappa
Ki-1 Antigen (CD30)
Ki-67
L-selectin, LECAM-1
See CD62L, above.
L26
See CD20, above.
Lambda
Laminin
Leukocyte Common Antigen, LCA
See CD45, above.
LN5
See Macrophage Marker, below.
Lutenizing Hormone
Lysozyme
Mac-1 (CD11b)
Macrophage Marker (LN5)
MAM-6, Human (Milk Fat Globular Protein)
Mart-1
Melanoma
See HMB45, above.
Milk Fat Globule
See Human Milk Fat Globule, above.
Monocytes
See CD14, above.
Myelin Basic Protein
Myoglobin
Myosin, Skeletal Muscle
Natural Killer Cells, NK cells
See CD Markers, above.
NCAM
See CD56, above.
Neuroblastoma
Neurofilament Protein
Neurophysin
NSE (Neuron Specific Enolase)
Ovarian Cancer Marker, CA125
p-53 Oncoprotein
P-glycoprotein (Multi Drug Resistance Marker)
P-Selectin
See CD62P, above.
p21, Ras Oncoprotein
Pan Cytokeratins
See Cytokeratin, above.
Pancreatic Amylase
See Amylase, above.
Pancreatic Polypeptide
Papilloma Virus (HPV)
Parathyroid Hormone
PCNA (Proliferating Cell Nuclear Antigen)
PECAM
See CD31, above.
PLAP
Pneumocystis Carinii
Progesterone
Progesterone Receptor (PR)
Prolactin
Prostate Specific Acid-Phosphatase (PSAP)
Prostate Specific Antigen (PSA)
Reed Sternberg Cells
See CD15, CD30, above.
Rhabdomyosarcoma
S-100 Protein
Secretin
Serotonin
Sialyl Lewis a
See CA19-9, above.
Somatostatin
Synaptophysin
Talin
TDT (Terminal Deoxynucleotidyl Transferase)
Tenascin
Testosterone
Thyroglobulin
Toxoplasma Gondii
Transferrin
Transferrin Receptor
See CD71, above.
Tubulin, alpha & beta (Blend)
Tubulin, alpha subunit
Tubulin, beta subunit
Tumor Associated Mucin Antigen (CA242)
Tumor Necrosis Factor (alpha subunit)
Tumor Necrosis Factor (beta subunit)
Ubiquitin
UCHL-1
See CD45RO, above.
Urokinase
Vasoactive Intestinal Polypeptide (VIP)
Vasopressin
VCAM
See CD106, above.
Villin
Vimentin
Vinculin
Vitamin D Receptor
Vitronectin
Von Willebrand Factor (VWF)
Von Willebrand Factor (VWF)
Isotype Controls
Mouse IgG Isotype Control 5ug/ml, Concentrate
Mouse IgG Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgG isotype primary antibodies.
Mouse IgG1 Isotype Control 5ug/ml, Concentrate
Mouse IgG1 Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgG1 isotype primary antibodies.
Mouse IgG2a Isotype Control 5ug/ml, Concentrate
Mouse IgG2a Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgG2a isotype primary antibodies.
Mouse IgG2b Isotype Control 5ug/ml, Concentrate
Mouse IgG2b Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgG2b isotype primary antibodies.
Mouse IgG3 Isotype Control 5ug/ml, Concentrate
Mouse IgG3 Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgG3 isotype primary antibodies.
Mouse IgM Isotype Control 5ug/ml, Concentrate
Mouse IgM Isotype Control 5ug/ml, Ready-To-Use
For use in parallel with mouse monoclonal IgM isotype primary antibodies.
Rabbit IgG Isotype Control Concentrate
Rabbit IgM Isotype Control Concentrate
Background Eradicators
BACKGROUND BUSTERBACKGROUND BUSTER
Eliminates non-specific binding in IHC, immunofluorescence, ELISA and flow cytometric assays. Allows staining of identical species antibodies and tissues (e.g. mouse antibody on mouse tissue). Short 10 minute incubation step prior to applying primary antibody. Shelf life 3 years. Store at 4°C.

CYTO-Q IMMUNO DILUENT & BLOCK
Antibody diluting, storage and blocking buffer ALL IN ONE. Prolongs antibody shelf life up to 4 years at 4°C. Simply dilute and refrigerate. Decreases and eradicates background. Increases antibody binding & allows higher antibody dilution for immunoassays. Antibodies remain wet on tissue for up to 36 hours. Shelf life 3 years. Store at 4°C.
Fc RECEPTOR BLOCKERFc RECEPTOR BLOCKER
Innovex Fc Receptor Blocker eliminates non-specific staining caused by Fc receptor staining in lymphoid and hematopoietic cells. Shelf life 3 years. Store at 4°C.
Fc RECEPTOR BLOCKER, AZIDE FREE
Innovative Support Reagents & Buffers
Enhancing Wash Buffers
See above.
Immuno Diluent and Block
See above.
Innovex Cyto-Blue (Permanent)
Blue cytoplasmic stain developed especially for counterstaining IHC nuclear stains of ER, PR, P53, PCNA, etc. Does not bind to nucleus. No masking of AEC or DAB stained nuclei occurs. Mountable with Innovex Probe Mount or xylene based mounting media.
Innovex Nuclear Red
Red color counterstain for IHC-BCIP/NBT stains, in-situ probes, and special stains. Mountable with xylene based media or Innovex Probe Mount. No fading with time.
Isotonic Buffered Saline (PBS)
An all purpose PBS for laboratory use. No preservatives. 20X concentrate, Store at 15-30°C. Shelf life 3 years.

STAT Aqua Hematoxylin (Permanent)
Allows for Stat nuclear counter and special staining in 10 seconds. Specially developed for IHC stains. Mountable with xylene and aqueous based mounting media. Stain does not fade with time, no precipitation,no filtration. Usable to the last drop. Shelf life 4 years. Store at 4°C.
TISSUE RECOVERY SOLUTION WITH BUILT-IN pH STABILIZER
Innovex's unique non-citrate formulation with built-in pH stabilizer provides optimal and gentle unmasking of antigens in the various heat methods (including high temp). Optimal pH remains constant regardless of temperature. Non-damaging to tissue morphology. Tissue does not slough off the slide. Shelf life 3 years. Store at 4°C.
Mounting Media

ADVANTAGE Permanent Mounting Media
Permanently preserves AEC, DAB, Fast Red and other immuno stains plus dye chemistry stains. Sets in 5 minutes at RT.

H&E MOUNT
Unique, permanent mounting media designed for coverslipping H&E stains from water or alcohol. Reduce time in eosin if cover slipping from water. Sets in 10 minutes.

PROBE MOUNT
Nuclear Fast Red stained specimens can be permanently mounted. Mount immunofluorescence & in-situ slides from water. Sets in 5 minutes.
Antigen Retrieval

UNI-TRIEVE
Retrieve easily and gently at 60°C for 30 minutes or 75°C for 15 minutes. Low temperature retrieval solution universally applicable to all antibodies and tissues. Also for IHC, Immunofluorescence, DNA & RNA probes. No Boiling. No High pH Buffer. No Citrate. Contains No Enzymes.
Multi-Tumor Control Slides
Breast Panel Multi-Tumor Control Slides
Each slide consists of five breast tumor tissues positive for ER, PR, Ki-67, BRST-2, E-Cadherin & Cytokeratins for Sentinel Nodes.
CD Markers Multi-Tumor Control Slides
Each slide contains Non-Hodgkins Lymphoma, Mantle Cell Lymphoma and Tonsil Tissues. Positive for 10 CD Markers: CD3, CD5, CD10, CD15, CD20, CD23, CD45, CD45A, CD45RO and Cyclin D1.
Core Panel Multi-Tumor Control Slides
Each slide includes: Brain, Thyroid, Lung, Muscle, Stomach, Bowel (Small & Large), Prostate, Kidney, Uterus, Liver, Pancreas, Breast and Skin.
Negative Control Sera
Chicken Negative Control Sera
For use in parallel with chicken primary antibodies.
Goat Negative Control Sera
For use in parallel with goat primary antibodies.
Mouse Negative Control Sera (ascites fluid)
For use in parallel with mouse monoclonal antibodies.
Rabbit Negative Control Sera
For use in parallel with rabbit primary antibodies.
Rat Negative Control Sera
For use in parallel with rat primary antibodies.
Sheep Negative Control Sera
For use in parallel with sheep primary antibodies.
SUBSTRATE/CHROMOGEN SYSTEMS

Turbo Action Stable Liquid DAB and AEC for Peroxidase (HRP) Staining
Fast Developing (1-5 minutes). Only 2 components. "Good to the last drop"; left over mixed AEC and DAB solution stable for up to 3 weeks. Stains 1200 slides.
Turbo Alkaline Phosphatase Chromogens
Fast Developing (5-10 minutes). Two components for Innovex Fast Red. Single solution for Permanent Innovex Brown (DAB like color) for alkaline phosphatase staining. Single solution for Permanent BCIP/NBT with no background or leeching out.
SIGNAL ENHANCING WASH BUFFERS
Alkaline Phosphatase-Enhancing Wash Buffer
(For amplifying Fast Red, BCIP/NBT, Innovex Brown & other substrate chromogens for alkaline phosphatase enzyme staining.)
Alkaline Phosphatase-Enhancing Wash Buffer
5X Concentrate
HRP-Enhancing Wash Buffer
5X Concentrate
HRP-Enhancing Wash Buffer
(For amplifying AEC & DAB Stains.)



